Calendula
Aseptic Calendula Stem Cell Lysate Rich in Antioxidant, Barrier-Supportive & Hydration-Enhancing Bioactives
Calendusome™ is a high-density plant stem cell lysate derived from Calendula officinalis, produced through controlled callus culture and aseptic biomanufacturing. It contains a rich spectrum of bioactive compounds naturally produced by calendula stem cells, including polyphenols, amino acids, osmolytes, and skin-supporting lipids.
This metabolite-rich profile helps support antioxidant defense, hydration balance, and skin barrier function, contributing to improved skin resilience, comfort, and a visibly healthy, radiant complexion.
INCI
Calendula Officinalis Callus Extract
Format
- Liquid
- Water-Soluble
- Pale Yellow
- Mild Scent
1-5%
Usage level
• 100% natural • Vegan • Made in the USA • cGMP-produced
What is Calendusome™?
Plant-derived exosomes are extracellular vesicles naturally produced by plant stem cells. They contain bioactive lipids, peptides, metabolites, and micro-molecules responsible for cellular signalling and regenerative responses.
Calendusome™ captures these bioactive components in a stable, concentrated format, delivering a metabolite-rich profile ideal for supporting antioxidant defense, hydration, skin barrier function, and overall skin resilience.
Key Benefits
Antioxidant Protection
Helps defend skin against oxidative stress and environmental aggressors through a high concentration of polyphenolic compounds.
Skin Barrier Support & Strengthening
Supports lipid balance and reinforces the skin’s natural protective barrier for improved resilience.
Hydration & Moisture Balance
Helps maintain optimal skin hydration through osmolytes and natural moisturizing factor components.
Skin Comfort & Soothing Support
Supports skin balance and helps reduce the appearance of irritation and sensitivity.
Anti-Glycation Support
Helps protect skin from glycation-related stress, supporting firmness and overall skin quality.
Radiance & Skin Vitality
Supports a healthy cellular environment associated with brighter, more radiant-looking skin.
Why Plant-Derived Exosomes?
| Feature | Calendusome (Calendula Stem Cell Lysate) | Synthetic Exosomes |
|---|---|---|
| Source | Calendula stem cell callus culture | Synthetic or engineered vesicle systems |
| Biological Intelligence | Naturally bioactive with complex metabolite signalling | Biomimetic structures with limited biological signalling |
| Ethical Profile | Vegan cruelty-free and clean-label | Ethical by design and non-biological |
| Immunogenicity | Non-immunogenic | Low immunogenic risk |
| Regulatory Status | Globally compliant | Generally compliant and formulation-dependent |
| Stability | High stability while maintaining bioactive complexity | High structural stability |
| Clean Beauty | Fully compatible | Compatibility depends on materials used |